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Full Catalog (page 1)
Product Number Product Name Molecular Formula Cas. No. Description Notes Alt. Name Alt. Name 2
BA 0001 7-Deaza-dA CEP C48H53N6O7P  107134-59-8  The N7 imidazole nitrogen of purine nucleosides is known to take part in non-Watson-Crick hydrogen bonding and in metal chelation. "Deleting" the N7 nitrogen by replacing it with a CH group is a useful modification that has been accomplished in DNA oligonucleotides using the phosphoramidite of 2'-deoxytubercidin, namely 7-Deaza-dA CEP.1, which was useful in showing that N7 of dA is an important hydrogen bond acceptor site for the endodeoxyribonuclease EcoRI.

1. (a) Seela, F.; Kehne, A. Biochemistry 1987, 26, 2232-2238. (b) Seela, F.; Berg, H.; Rosemeyer, H. Biochemistry 1989, 28, 6193-6198. 		 Useful for modification of base pairing and metal chelating characterisitcs of purine nucleosides through elimination of the N7nitrogen.

 		 N6-Benzoyl-7-deaza-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine   
BA 0002 N6-Methyl-dA
CEP		 C41H50N7O6P  105931-58-6      3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-N6-methyl-2'-deoxyadenosine   
BA 0003 3'-dA CEP C47H52N7O7P  207347-42-0      N6-Benzoyl-2'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-3'-deoxyadenosine   
BA 0004 8-Bromo-dA CEP C43H52BrN8O6P  207906-54-5      8-Bromo-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-N6-(dimethylaminomethylidene)-2'-deoxyadenosine   
BA 0005 8-Oxo-dA CEP C47H52N7O8P  142979-42-8      N6-Benzoyl-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-8-oxo-2'-deoxyadenosine   
BA 0007 5-Fluoro-O4-TMP-dU
CEP		 C48H56FN4O8P  198080-36-3    The convertible nucleoside 5-Fluoro-O4-TMP-dU CEP allows the formation of N4-alkyl-5-fluoro-dC residues by reaction with an alkyl amine.

 		 3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-deoxyuridine   
BA 0008 7-Deaza-dG CEP C44H54N7O7P  121767-97-3 

G-Rich regions in nucleic acids often display disrupted Watson-Crick base-pairing due to the ability of dG and G residues to enter into non-Watson-Crick inter- and intramolecular hydrogen bonding. A solution to this problem is to replace the N7 nitrogen atom on the guanine nucleobase with a CH group, obviating the possibility of hydrogen bonding at that position. For studies on alternating d(G-C)3 and d(C-G)3 hexanucleotides containing 7-deaza-2'-deoxyguanosine or 8-aza-7-deaza-2'-deoxyguanosine (BA 0242) in place of dG, see: Seela, F.; Driller, H. Nucleic Acids Res. 1989, 17(3), 901-910. We also now offer 7-Deaza-G CEP (BA 0323) for RNA synthesis. 

 Installation of 7-Deaza-dG residues in G-rich regions can disrupt unwanted hydrogen bonding.  7-Deaza-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-N2-(dimethylaminomethylidene)-2'-deoxyguanosine   
BA 0009 8-Bromo-dG CEP C43H52BrN8O7P  198080-37-4      8-Bromo-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-N2-(dimethylaminomethylidene)-2'-deoxyguanosine   
BA 0010 8-Oxo-dG CEP C44H54N7O9P  143060-53-1      3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-N2-isobutyryl-8-oxo-2'-deoxyguanosine   
BA 0011 4-Thio-dT CEP C43H52N5O7PS  None found      4-Thio-T CEP  S-(2-Cyanoethyl)-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-4-thiothymidine 
BA 0012 Carboxy-dT CEP C43H51N4O10P  198080-38-5      5-(E-2-Carbomethoxyvinyl)-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine   
BA 0013 2-Thio-dT CEP C48H55N4O8PS  156783-23-2 and 156783-15-2      2-Thio-T CEP  3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-N3/O4-toluyl-2-thiothymidine 
BA 0014 Biotin-dT CEP C69H89N8O12PS  198080-40-9      5-[E-2-[N-[N-[N1-(4-t-Butylbenzoyl)-D-(+)-biotinyl]-6-aminohexyl]carboxamido]vinyl]-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine   
BA 0015 Amino-modifier-C6-dT CEP C50H62F3N6O10P  210534-16-0      3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5-[E-2-[N-[6-(trifluoroacetamido)hexyl]carboxamido]vinyl]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine   
BA 0016 2'-Deoxynebularine CEP C40H47N6O6P  178925-28-5      3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxynebularine   
BA 0017 O6-Phenyl-dI
CEP		 C46H51N6O7P  133471-07-5    The convertible nucleoside O6-Phenyl-dI CEP allows the formation of N6-alkyl-dA residues through reaction with alkyl amines.  3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-O6-phenyl-2'-deoxyinosine   
BA 0021 2-Aminopurine CEP C43H53N8O6P  178925-41-2         
BA 0030 5’-Amino-modifier-5 CEP C33H44N3O4P  612548-86-4         
BA 0031 Spacer-9 CEP C36H49N2O7P  146668-73-7         
BA 0032 Spacer-C3 CEP C33H43N2O5P  110894-23-0         
BA 0033 dSpacer CEP C35H45N2O6P  129821-76-7         
BA 0034 5’-Amino-modifier-C6-TFA
CEP		 C17H31F3N3O3P  133975-85-6         
BA 0036 5’-Amino-modifier-C3-TFA
CEP		 C14H25F3N3O3P  853955-89-2         
BA 0037 Thiol-modifier-C6-S-S
CEP		 C42H61N2O5PS2  148254-21-1         
BA 0038 Biotin-TEG CEP C52H76N5O11PS  198080-44-3         
BA 0039 Cholesteryl-TEG CEP C70H106N3O11P  873435-29-1