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Full Catalog (page 15)
Product Number Product Name Molecular Formula Cas. No. Description Notes Alt. Name Alt. Name 2
PR 3310 8-Bromo-5'-O-(dimethyoxytrityl)-
N2-(dimethyl-aminomethylidene)-
2'-deoxyguanosine
C34H35BrN6O6  204582-53-6         
PR 3320 8-Bromo-N6-
(dimethylaminomethylidene)-2'-
deoxyadenosine
C13H17BrN6O3  207906-52-3         
PR 3330 8-Bromo-N2-
(dimethylaminomethylidene)-2'-
deoxyguanosine
C13H17BrN6O4  717876-75-0         
PR 3335 5'-O-Dimethoxytrityl-N6-
(dimethylaminomethylidene)-8-
ethenyl-2'-deoxyguanosine
C36H38N6O6  1101864-07-6  Versatile synthetic intermediate for the preparation of a variety of photochromic nucleosides (PCNs).1,2

1. Ogasawara, S.; Saito, I.; Maeda, M. Tet. Lett., 2008, 49, 2479-82.

2. Ogasawara, S.; Maeda, M. Angew. Chem. Int. Ed., 2008, 47, 8839-42. 
     
PR 3340 8-Bromo-5'-O-(dimethoxytrityl)-
N6-(dimethylaminomethylidene)-
2'-deoxyadenosine
C34H35BrN6O5  207906-53-4         
PR 3350 3'-O-(t-Butyldimethylsilyl)-5'-
oxo-2'-deoxy-8,5'-cycloadenosine
C16H23N5O3Si  None         
PR 3360 5'-Chloro-5'-deoxyadenosine C10H12ClN5O3  892-48-8         
PR 3370 6-Chloro-9-(β-D-2-
deoxyribofuranosyl)purine
C10H11ClN4O3  4594-45-0         
PR 3380 6-Chloro-9-(3,5-O-di-(p-
toluoyl)-β-D-2-deoxyribofuranosyl)
purine
C26H23ClN4O5  91713-46-1  Useful synthon for preparation of 6-substituted purine 2'-deoxyribosides.       
PR 3390 6-Chloro-9-(5-O-dimethoxytrityl-
β-D-2-deoxyribofuranosyl)
purine
C31H29ClN4O5  133931-96-1         
PR 3400 6-Chloro-9-(β-D-ribofuranosyl)
purine
C10H11ClN4O4  5399-87-1         
PR 3410 (5'S)-8,5'-Cycloadenosine C10H11N5O4  41432-67-1         
PR 3420 (5'S)-2'-Deoxy-8,5'-
cycloadenosine
C10H11N5O3  117182-88-4         
PR 3430 3'-Deoxyadenosine C10H13N5O3  73-03-0      Cordycepin   
PR 3440 5'-Deoxy-8,5'-cycloadenosine C10H11N5O3  3415-89-2         
PR 3445 2'-Deoxyadenosine Monohydrate C10H13N5O3  958-09-8         
PR 3450 2'-Deoxy-4-desmethylwyosine C13H15N5O4  101803-00-3  A convenient synthon for the preparation on N-2-alkyl derivatives of 2'-deoxyguanosine: Ueda, T, et al., Nucleosides & Nucleotides, 1985, 4, 595-606.       
PR 3452 2'-Deoxyguanosine C10H13N5O4  961-07-9         
PR 3455 α-2'-Deoxyguanosine C10H13N5O4  19916-78-0         
PR 3460 3'-Deoxyguanosine C10H13N5O4  3608-58-0         
PR 3463 2'-Deoxyinosine C10H12N4O4  890-38-0         
PR 3465 2'-Deoxyisoguanosine C10H13N5O4  106449-56-3  The transposition of atoms or groups in the purine nucleobase of G/dG provides isomers that have altered base-pairing capabilities.We offer a family of guanosine isomers in nucleoside and phosphoramidite forms.

Isoguanosines are important in the field of non-natural base pairing. In 1989, Benner and co-workers1 reported the enzymatic incorporation of iso-G into RNA and DNA and characterized the distinct non-natural base pairing that resulted, especially pairing involving the similarly transposed isomer of dC known as iso-dC (we offer the closely-related compound 5-Methyliso-dC, PY 7255

Iso-G and Iso-dG are part of a family that includes Guanosine (PR 3703) , 2'-Deoxyguanosine (PR 3452) , the isomeric nucleosides 2'-Deoxypseudoguanosine (Pseudo-dG, PRA 10103) , 2'-Deoxypseudoisoguanosine (Pseudoiso-dG, PRA 10104) and the phosphoramidites Pseudo-dG CEP (BA 0312) and Pseudoiso-dG CEP (BA 0314)

Learn more about these novel compounds and their use by downloading a Product Information sheet for our family of guanosine isomers

1. Switzer, C. Y.; Moroney, S. E.; Benner, S. A. J. Am. Chem. Soc. 1989, 111, 8322-8323.

 

Isoguanosine (Iso-G, PR 3735) and 2'-Deoxyisoguanosine (Iso-dG, PR 3465) are isomeric with G/dG, differing by transposition of the carbonyl group at position 6 of G or dG with the C-NH2 group at position 2, providing a novel hydrogen bond donor/acceptor pattern.

 
Iso-dG  2-Oxo-2'-deoxyadenosine 
PR 3470 2'-Deoxynebularine C10H12N4O3  4546-68-3         
PR 3480 3',5'-Di-O-acetyl-2'-
deoxyinosine
C14H16N4O6  106568-79-0         
PR 3490 3',5'-Di-O-acetyl-O6-phenyl-
2'-deoxyinosine
C20H20N4O6  133471-06-4         
PR 3495 2',3'-Dideoxyadenosine C10H13N5O2  4097-22-7