Berry & Associates, Inc.

Full Catalog pages: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26

Full Catalog (page 19)
Product Number	Product Name	Molecular Formula	Cas. No.	Description	Notes	Alt. Name	Alt. Name 2
PRA 10050	7-Deaza-2'-deoxyxanthosine	C11H13N3O5	96022-82-1
PRA 10055	5'-O-(Dimethoxytrityl)-7-deaza-2'- deoxyxanthosine	C32H31N3O7	869355-16-8
PRA 10060	1-(β-D-2-Deoxyribofuranosyl)-5- nitroindole	C13H14N2O5	191421-10-0
PRA 10070	1-(β-D-2-Deoxyribofuranosyl)-4- methylindole	C14H17NO3	180420-84-2		This product has been discontinued.
PRA 10080	1-(5-O-(Dimethoxytrityl)-β-D-2- deoxyribofuranosyl)-4-methylindole	C35H35NO5	180737-32-0		This product has been discontinued.
PRA 10090	1-(5-O-(Dimethoxytrityl)-β-D-2- deoxyribofuranosyl)-5-nitroindole	C34H32N2O7	869355-18-0
PRA 10095	5-Iodotubercidin	C11H13IN4O4	24386-93-4	Competitive inhibitor of MAP kinase ERK2. Also inhibits insulin receptor kinase, adenosine kinase, and various serine and threonine kinases. Soluble in DMSO.		7-Deaza-7-iodoadenosine	ITU
PRA 10100	5'-O-(Dimethoxytrityl)-N²- (dimethylaminomethylidene)-7-deaza- 2'-deoxyguanosine	C35H37N5O6	111869-42-2
PRA 10103	2'-Deoxypseudoguanosine	C10H13N5O4	912814-74-5	The transposition of atoms or groups in the purine nucleobase of G/dG provides isomers that have altered base-pairing capabilities. We offer a family of guanosine isomers in nucleoside and phosphoramidite forms. Pseudo-dG (PRA 10103) is a guanosine isomer that was recently reported by Hosmane and co-workers.¹ We also offer Pseudo-dG CEP (BA 0312) , which may be used to incorporate Pseudo-dG nucleotides into DNA. Pseudo-dG and Pseudo-dG CEP are part of a family that includes Guanosine (PR 3703) , 2'-Deoxyguanosine (PR 3452) , the isomeric nucleosides Isoguanosine (Iso-G, PR 3735) , 2'-Deoxyisoguanosine (Iso-dG, PR 3465) , 2'-Deoxypseudoisoguanosine (Pseudoiso-dG, PRA 10104) , and the phosphoramidite Pseudoiso-dG CEP (BA 0314). Learn more about these novel compounds and their use by downloading a Product Information sheet for our family of guanosine isomers . 1. Ujjinamatada, R. K.; Paulman, R. L.; Ptak, R. G.; Hosmane, R. S. Bioorg. Med. Chem. 2006, 14, 6359-6367. See also: Ujjinamatada, R. K.; Phatak, P.; Burger, A. M.; Hosmane, R. S. J. Med. Chem. 2008, 51, 694-698.	2'-Deoxypseudoguanosine (Pseudo-dG) is related to dG by transposition of the nitrogen atom at position 3 and the C-NH₂ group at position 2 of the nucleobase, providing a novel hydrogen bond donor/acceptor pattern.	Pseudo-dG
PRA 10104	2'-Deoxypseudoisoguanosine	C10H13N5O4	912814-75-6	The transposition of atoms or groups in the purine nucleobase of G/dG provides isomers that have altered base-pairing capabilities. We offer a family of guanosine isomers in nucleoside and phosphoramidite forms. Pseudoiso-dG (PRA 10104) is a guanosine isomer that was recently reported by Hosmane and co-workers.¹ We also offer Pseudoiso-dG CEP (BA 0314) , which may be used to incorporate Pseudoiso-dG nucleotides into DNA. Pseudoiso-dG and Pseudoiso-dG CEP are part of a family that includes Guanosine (PR 3703), 2'-Deoxyguanosine (PR 3452), the isomeric nucleosides Isoguanosine (Iso-G, PR 3735), 2'-Deoxyisoguanosine (Iso-dG, PR 3465), 2'-Deoxypseudoguanosine (Pseudo-dG, PRA 10103), and the phosphoramidite Pseudo-dG CEP (BA 0312). Learn more about these novel compounds and their use by downloading a Product Information sheet for our family of guanosine isomers . 1. Ujjinamatada, R. K.; Paulman, R. L.; Ptak, R. G.; Hosmane, R. S. Bioorg. Med. Chem. 2006, 14, 6359-6367. See also: Ujjinamatada, R. K.; Phatak, P.; Burger, A. M.; Hosmane, R. S. J. Med. Chem. 2008, 51, 694-698 and Berry, D. A.; Wotring, L. L.; Drach, J. C.; Townsend, L. B. Nucleosides Nucleotides 1994, 13, 2001-2011.	2'-Deoxypseudoisoguanosine (Pseudoiso-dG) is related to Iso-dG by transposition of the nitrogen atom at position 3 and the C-NH₂ group at position 2 of the nucleobase, providing a novel hydrogen bond donor/acceptor pattern. It is also related to 2'-Deoxypseudoguanosine (Pseudo-dG) by transposition of the C-NH₂ group at position 3 and the carbonyl group at position 6.	Pseudoiso-dG
PRA 10110	N²-(Dimethylaminomethylidene)- 7-deaza-2'-deoxyguanosine	C14H19N5O4	111902-68-2
PRA 10120	9-Deaza-2'-deoxyguanosine	C11H14N4O4	224946-77-4			2-Amino-7-(β-D-2-deoxyribofuranosyl)pyrrolo[3,2-d]pyrimidin-4-one
PRA 10130	9-Deazaguanosine	C11H14N4O5	102731-45-3			2-Amino-7-(β-D-ribofuranosyl)[3,2-d]pyrimidin-4-one
PRA 10140	Sangivamycin	C12H15N5O5	18417-89-5			4-Amino-7-(β-D-ribofuranosyl)-pyrrolo[2,3-d]pyrimidine-5-carboxamide
PRA 10150	Toyocamycin	C12H13N5O4	606-58-6	Further discounts available for larger orders. Pricing shown is for toyocamycin obtained from fermentation. We also offer synthetic toyocamycin, $325.00 (25 mg); $995.00 (100 mg). Soluble in acetic acid and acidic solution. Moderately soluble in water, methanol, and ethanol.		4-Amino-5-cyano-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine	Vengicide
PRA 10160	Triciribine	C13H16N6O4	35943-35-2	Triciribine (a.k.a. TCN, Tricyclic Nucleoside, NSC-154020) inhibits Akt (protein kinase B) in a very selective fashion, resulting in apoptosis in human cancer cells (Yang L, Dan HC, Sun M Liu Q, Sun X-m, Feldman RI, Hamilton AD, Polokoff M, Nicosia SV, Herlyn M, Sebti SM, Cheng JQ, Cancer Research 2004, 64, 4394-4399). It also inhibits DNA synthesis (Wotring LL, Townsend LB, et. al, Cancer Res. 1990, 50, 4891-9), and as its monophosphate, is active against HIV type 1 (Ptak RG, Borysko KZ, Porcari AR, Buthod JL, Holland LE, Shipman C Jr, Townsend LB, Drach JC. AIDS Res. Hum. Retroviruses 1998, 14, 1315-22).	Triciribine is a tricyclic nucleoside that is cell-permeable and inhibits phosphorylation, activation and signalling of Akt.	Tricyclic Nucleoside, TCN	(6-Amino-4-methyl-8-(β-D-ribofuranosyl)-4H,8H-pyrrolo[4,3,2-de]pyrimido[4,5-c]pyridazine)
PRA 10162	Tricyclic Nucleoside Phosphate	C13H17N6O7P	61966-08-3	May be useful in treating cancers with tumors that overexpress Akt, shows antiviral, antineoplastic activity, inhibits enzymes in de novo purine nucleotide synthesis.^1,2 (1) Porcari, A. R.; Ptak, R. G.; Borysko, K. Z.; Breitenbach, J. M.; Drach, J. C.; Townsend, L. B. Nucleosides, Nucleotides & Nucl. Acids 2003, 22(12), 2171-2193. (2) Moore, E. C.; Hurlbert, R. B.; Boss, G. R.; Massia, S. P. Biochem. Pharmcol. 1989, 38(22), 4045-4051.	Inhibits Akt phosphorylation.	TCN-P, Triciribine Phosphate	6-Amino-4-methyl-8-(β-D-ribofuranosyl)-4H,8H-pyrrolo[4,3,2-de]pyrimido[4,5-c]pyridazine 5'-monophosphate
PRA 10170	8-Aza-7-deaza-2'-deoxyguanosine	C10H13N5O4	100644-70-0			PPG
PRA 10175	6-Amino-2-(2-deoxy-β-D- ribofuranosyl)-2,5-dihydro-4H- pyrazolo-[3,4-d]-pyrimidin-4- one	C10H13N5O4	109737-94-2			iso-PPG
PS 5000	4'-Chloromethyl-4,5',8- trimethylpsoralen (3-Chloromethyl- 2,5,9-trimethyl-7H-furo[3,2-g] [1]benzopyran-7-one)	C15H13ClO3	62442-57-3	Nucleophilic displacement of the chloro substituent at the 4' position allows one to attach various linkers to the psoralen ring system.	Useful building block for incorporation of the psoralen ring system.
PS 5005	4'-Aminomethyl-4,5',8- trimethylpsoralen	C15H15NO3	64358-50-5			4'-Aminomethyltrioxsalene
PS 5010	4'-(2-Hydroxyethoxy)methyl-4,5',8- trimethylpsoralen	C17H18O5	78318-60-2			3-(2-Hydroxyethoxy)methyl-2,5,9-trimenthyl-7H-furo[3,2-g][1]benzopyran-7-one
PS 5020	4'-(6-Hydroxyhexyloxy)methyl- 4,5',8-trimethylpsoralen(3-(6- hydroxyhexyloxy)methyl-2,5,9- trimethyl-7H-furo[3,2-g]-[1] benzopyran-7-one)	C21H26O5	869308-45-2
PS 5025	4'-Hydroxymethyl-4,5'-8- trimethylpsoralen (HMT)	C15H14O4	62442-59-5		Intercalates into and photoalkylates dsDNA, primarily at thymidine sites. May be useful for targeted mutagenesis and photochemotherapy.	3-(Hydroxymethyl)-2,5,9-trimethyl-7H-furo[3,2-g][1]benzopyran-7-one)	4'-Hydroxymethyltrioxsalen
PY 7000	2'-O-Acetyl-5'-O-benzoyl-5- methyl-3'-deoxyuridine	C19H20N2O7	143653-60-5
PY 7010	N⁴-Acetyl-5'-O- (dimethoxytrityl)-5-methyl-2'-O- methylcytidine	C34H37N3O8	869355-20-4		This product has been discontinued.