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Product Number Product Name Molecular Formula Cas. No. Description Notes Alt. Name Alt. Name 2
BA 0098 5,6-Dihydro-dU CEP C39H49N4O8P  None found         
BA 0099 (5S)-5,6-Dihydro-dT CEP C40H51N4O8P  113901-09-0 

For leading references, please see: 1) Cohn, W.E.; Doherty, D.E. J. Am. Chem. Soc.  1956, 78 , 2863-2866; 2) Schuldhof, J.C.; Molko, D.; Teoule, R. Nucleic Acids Res. 1988, 16, 319-326; 3) Barvian, M.R.; Greenberg, M.M. J. Org. Chem. 1995, 60, 1916-1917. 

 

  5,6-Dihydro-T CEP   
BA 0106 Diaminopyrazine-C-nucleoside CEP C57H82ClN8O6P  None found    This product has been discontinued.     
BA 0107 Fluorescein-dT CEP C79H89N6O17P  289712-99-8         
BA 0109 (5’S)-8,5’-Cyclodeoxyadenosine
5’-O-CEP
C28H47N8O4PSi  None found 

8,5’-Cyclodeoxyadenosine (cyclo-dA) is a naturally occurring free-radical-induced DNA lesion. This bulky lesion has been shown to be present in human cells.1 Cyclo-dA is a strong block to gene expression in both CHO and human cells but can be repaired via nucleoside excision repair mechanisms, but not by base excision repair mechanisms.2 Our (5’S)-8,5’-Cyclodeoxyadenosine 5’-O-CEP can be used for efficient incorporation of cyclo-dA into oligonucleotides.

For additional information, download a Product Information Sheet.

(1) Dizdaroglu, M.; Dirksen, M.L.; Jiang, H.X.; Robbins, J.H. J. Biochem. 1987, 241, 929-932.

(2) Brooks, P.J.; Wise, D.S.; Berry, D.A.; Kosmoski, J.V.; Smerdon, M.J.; Somers, R.L.; Mackie, H.; Spoonde, A.Y.; Ackerman, E.J.; Coleman, K.; Tarone, R.E.; Robbins, J.H. J. Biol. Chem. 2000, 275 , 22355-22362.

 

 
This 5’-O phosphoramidite is intended for incorporation into DNA via 5’ to 3’ synthesis.     
BA 0112 4-Thio-dU CEP C42H50N5O7PS  144303-74-2         
BA 0113 6-Thio-dG CEP C45H50F3N8O7PS  146691-59-0         
BA 0118 2-Amino-dA CEP C58H83N10O6P  None found      2,6-Diaminopurine-2'-deoxyriboside CEP   
BA 0119 5'-Amino-dT CEP C39H48N5O7P  194034-71-4      5'-Amino-T CEP   
BA 0122 TAMRA-dT CEP C73H83N8O13P  None found      Tetramethylrhodamine-dT CEP   
BA 0123 DNP-TEG CEP C48H64N5O13P  1027512-01-1         
BA 0124 5-Bromo-dC CEP C46H51BrN5O8P  178925-43-4         
BA 0128 5'-O-Methyl-dT CEP C20H33N4O6P  149681-62-9      5'-O-Methyl-T CEP   
BA 0129 Puromycin CPG N/A  N/A         
BA 0130 3’-TAMRA CPG N/A  N/A      3'-Tetramethylrhodamine CPG   
BA 0131 5-Hydroxy-dU CEP C41H49N4O10P  197229-19-9         
BA 0132 N4-Ethyl-dC
CEP
C41H52N5O7P  195535-80-9         
BA 0134 Spacer-C12 CEP C42H61N2O5P  158665-27-1         
BA 0135 Dabcyl-dT CEP C63H76N9O10P  316121-62-7         
BA 0138 EDTA-C2-dT CEP C60H81N8O16P  None found         
BA 0139 3'-Fluorescein-dT CPG N/A  N/A         
BA 0143 2'-Deoxypseudouridine CEP C39H47N4O8P  289712-98-7         
BA 0144 7-Deaza-2'-deoxyxanthosine CEP C40H47N6O8P  676456-10-3         
BA 0145 2'-O-Methyl-5-bromo-U CEP C40H48BrN4O9P  None found         
BA 0146 5’-Dabcyl CEP C30H45N6O3P  288631-58-3         
BA 0147 3'-Fluorescein CPG N/A  N/A      3’-(6-FAM) CPG