
Full Catalog pages: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
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| Product Number | Product Name | Molecular Formula | Cas. No. | Description | Notes | Alt. Name | Alt. Name 2 |
| BA 0098 | 5,6-Dihydro-dU CEP | C39H49N4O8P | None found | ||||
| BA 0099 | (5S)-5,6-Dihydro-dT CEP | C40H51N4O8P | 113901-09-0 | For leading references, please see: 1) Cohn, W.E.; Doherty, D.E. J. Am. Chem. Soc. 1956, 78 , 2863-2866; 2) Schuldhof, J.C.; Molko, D.; Teoule, R. Nucleic Acids Res. 1988, 16, 319-326; 3) Barvian, M.R.; Greenberg, M.M. J. Org. Chem. 1995, 60, 1916-1917.
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5,6-Dihydro-T CEP | ||
| BA 0106 | Diaminopyrazine-C-nucleoside CEP | C57H82ClN8O6P | None found | This product has been discontinued. | |||
| BA 0107 | Fluorescein-dT CEP | C79H89N6O17P | 289712-99-8 | ||||
| BA 0109 | (5’S)-8,5’-Cyclodeoxyadenosine 5’-O-CEP |
C28H47N8O4PSi | None found | 8,5’-Cyclodeoxyadenosine (cyclo-dA) is a naturally occurring free-radical-induced DNA lesion. This bulky lesion has been shown to be present in human cells.1 Cyclo-dA is a strong block to gene expression in both CHO and human cells but can be repaired via nucleoside excision repair mechanisms, but not by base excision repair mechanisms.2 Our (5’S)-8,5’-Cyclodeoxyadenosine 5’-O-CEP can be used for efficient incorporation of cyclo-dA into oligonucleotides. For additional information, download a Product Information Sheet.(1) Dizdaroglu, M.; Dirksen, M.L.; Jiang, H.X.; Robbins, J.H. J. Biochem. 1987, 241, 929-932. (2) Brooks, P.J.; Wise, D.S.; Berry, D.A.; Kosmoski, J.V.; Smerdon, M.J.; Somers, R.L.; Mackie, H.; Spoonde, A.Y.; Ackerman, E.J.; Coleman, K.; Tarone, R.E.; Robbins, J.H. J. Biol. Chem. 2000, 275 , 22355-22362.
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