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BA 0008
Product Information Molecular Structure

7-Deaza-dG CEP

Notes: Installation of 7-Deaza-dG residues in G-rich regions can disrupt unwanted hydrogen bonding.

Description: 

G-Rich regions in nucleic acids often display disrupted Watson-Crick base-pairing due to the ability of dG and G residues to enter into non-Watson-Crick inter- and intramolecular hydrogen bonding. A solution to this problem is to replace the N7 nitrogen atom on the guanine nucleobase with a CH group, obviating the possibility of hydrogen bonding at that position. For studies on alternating d(G-C)3 and d(C-G)3 hexanucleotides containing 7-deaza-2'-deoxyguanosine or 8-aza-7-deaza-2'-deoxyguanosine (BA 0242) in place of dG, see: Seela, F.; Driller, H. Nucleic Acids Res. 1989, 17(3), 901-910. We also now offer 7-Deaza-G CEP (BA 0323) for RNA synthesis.

7-Deaza-dG CEP
Product Details Product Pricing

MF: C44H54N7O7P

MW: 823.92

CAS NO: 121767-97-3

Storage Conditions: -20 oC, dry

Purity≥95%

Availability: 

Stock maintained. Ships within 1-3 days.

Alternate Name: 

7-Deaza-3'-O-[(diisopropylamino)(2-cyanoethoxy)
phosphino]-5'-O-(4,4'-dimethoxytrityl)-N2-
(dimethylaminomethylidene)-2'-deoxyguanosine
Unit Weight Unit Price Quantity
100 µmol $355.00
0.25 g $975.00
 
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