5'-Fluorescein CEP
Notes: Useful for the installation of fluorescein at the 5'-terminus of an
oligonucleotide.
Description: For the installation of fluorescein at the 5'-terminus of an
oligonucleotide, the phosphoramidite "6-FAM"
(5'-Fluorescein CEP, BA
0054), is a popular choice. The lack of a trityl group precludes
multiple additions or assaying the coupling step. For those
interested in a trityl-bearing version of 6-FAM, we offer
Fluorescein II CEP ("6-FAM II", BA
0253), which features the same tether length as 6-FAM, but
includes a DMT group, and Fluorescein III CEP ("6-FAM III", BA
0334) with a DMT on a 1,3-diol framework.
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