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BA 0201
Product Information Molecular Structure

5-Methyl-2'-deoxyzebularine CEP

Notes: A fluorescent nucleoside useful for probing the characterisitcs of DNA repair complexes.

Description: 

5-Methyl-2'-deoxyzebularine or m5K, is an intrinsically fluorescent nucleoside that, upon incorporation into oligonucleotides,1,2 allows the characterization of the assembly of RecA-ssDNA complexes that initiate DNA repair responses.2 Further, deletion of the C4 amino group of dC allows dissection of the roles of various hydrogen bonds, and the incorporation of 2-pyrimidinone residues into DNA allows the formation of abasic sites at selected positions after mild acid hydrolysis.3 See also a ribo version, Zebularine CEP (BA 0254).

1. Gildea, B.; McLaughlin, L. W. Nucleic Acids Res. 1989, 17(6), 2261-2281.
2. Singleton, S. F. et al., Organic Lett. 2001, 3, 3919-3922.
3. Iocono, J. A.; Gildea, B.; McLaughlin, L. W.,Tetrahedron Lett. 1990, 31, 175-178.

5-Methyl-2'-deoxyzebularine CEP
Product Details Product Pricing

MF: C40H49N4O7P

MW: 728.81

CAS NO: 125258-62-0

Storage Conditions: -20 oC, dry

Purity≥95%

Availability: 

Stock maintained. Ships within 1-3 days.

Unit Weight Unit Price Quantity
3 g minimum order, call for pricing $0.00
 
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