BBQ-650 Nhydroxysuccinimide ester
Notes: Dark quencher of long-wavelength fluorescence. Description: Our BlackBerry® quenchers are excellent quenchers of long-wavelength
fluorophores in both FRET and contact modes. They exhibit an absorption maximum
at ca. 650 nm and have useful absorbance between 550 and 750 nm. The tricyclic
8-alkoxyjulolidine moiety is a powerful pi-donor that affords a surprising
bathochromic shift when compared to related compounds. A key advantage of the
BBQ-650 is its stability to ammonia and oxidation conditions. We offer versions
for incorporation into oligonucleotides at the 3'-terminus (3'-BBQ-650
CPG, BL 2010), internally (BBQ-650-dT
CEP, BL 1010), or at the 5'-terminus (5'-BBQ-650
CEP, BL 1020 and 5'-BBQ-650(DMT)
CEP, BL 1030). In addition, this BBQ-650 NHS Ester (BL
3010) is available for postsynthetic labeling of
amine-modified oligonucleotides.
Download a product information sheet for BL 3010 here.
Download a brief overview of BlackBerry Quenchers here.
1.Valanne, A.; Malmi, P.; Appelblom, H.;
Niemelä, P.; Soukka, T. Anal.
Biochem. 2008, 375, 71-81. |
