5'-BBQ-650 CEP

Notes: For installation of a BlackBerry™ quencher at the 5'-terminus of an oligonucleotide.

Description: Our BlackBerry® quenchers are excellent quenchers of long-wavelength fluorophores in both FRET and contact modes. They exhibit an absorption maximum at ca. 650 nm and have useful absorbance between 550 and 750 nm. The tricyclic 8-alkoxyjulolidine moiety is a powerful pi-donor that affords a surprising bathochromic shift when compared to related compounds. A key advantage of the BBQ-650 is its stability to ammonia and oxidation conditions. We offer versions for incorporation into oligonucleotides at the 3'-terminus (3'-BBQ-650 CPG, BL 2010), internally (BBQ-650-dT CEP, BL 1010), or at the 5'-terminus (5'-BBQ-650 CEP, BL 1020 and 5'-BBQ-650(DMT) CEP, BL 1030). In addition, BBQ-650 NHS Ester (BL 3010) is available for postsynthetic labeling of amine-modified oligonucleotides.

Download a brief overview of these dark quenchers of long-wavelength fluorescence here.

Download a Product Information sheet for BL 1020 here.