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FL 1360
Product Information Molecular Structure

F-CPR-II CEP

Notes: For the chemical phosphorylation of oligonucleotides with concomitant fluorous affinity purification. Learn about fluorous affinity purification of oligonucleotides here or download a brief overview here.

Description: Download Product Information. Fluorous Chemical Phosphorylation Reagent II (F-CPR-II CEP) allows a combination of fluorous affinity purification with concomitant 5'-phosphorylation, which is especially attractive when synthesizing longmers that will be used in ligase reactions. Further, if a 5'-phosphate is tolerated in a particular application, F-CPR-II may be used as a common handle for fluorous purification, obviating the need to choose a different fluorous phosphoramidite for each different 5'-terminal nucleotide. F-CPR-II CEP is used in the same way as CPR-II (Guzaev, A., et al., Tetrahedron 1995, 51, 9375-9384; US Patent 5,959,090, assignee Glen Research), i.e., a 6 minute coupling with no capping. Use with Fluoro-Pak™ Columns (FP 7210 or FP 7220) and Loading Buffer (LB 7100); see "Fluorous Purification of Oligonucleotides". The final retro-aldol cleavage to afford the free 5'-phosphorylated oligonucleotide is achieved in the same fashion as found for CPR-II.

F-CPR-II CEP
Product Details Product Pricing

MF: C49H54F17N2O9P

MW: 1168.91

CAS NO: 1027512-47-5

Storage Conditions: Dry, -20 C

Purity≥95%

Availability: 

Stock maintained. Ships within 1-3 days.

Alternate Name: 

Fluorous chemical phosphorylation reagent II

Alternate Name: 

2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-
cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-
(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-
propanediol
Unit Weight Unit Price Quantity
100 µmol $105.00
250 µmol $175.00
 
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