Fluorous dabcyl N-hydroxysuccinimide ester
Notes: Allows researchers to study the benefits of fluorous effects on purification and probe performance at various positions of oligonucleotides and peptides. Description: We have also studied dabcyls that bear a fluorous tail tethered to the aniline nitrogen atom. Dabcyl NHS ester is useful for the installation of dabcyl residues into amine-modified oligonucleotides or amine-bearing peptides. Fluorous dabcyl NHS ester has a fluorous tail attached to the aniline nitrogen via a two-methylene insulator. This insulation assures that the absorption maximum of dabcyl is not greatly affected. The corresponding fluorous dabcyl carboxylic acid has an absorption maximum at 414 nm in
methanol, which compares to a value of 420-425 for dabcyl itself.
Learn about fluorous affinity purification of oligonucleotides here. Download a brief overview here.
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