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PRA 10103
Product Information Molecular Structure

2'-Deoxypseudoguanosine

Notes: 

2'-Deoxypseudoguanosine (Pseudo-dG) is related to dG by transposition of the nitrogen atom at position 3 and the C-NH2 group at position 2 of the nucleobase, providing a novel hydrogen bond donor/acceptor pattern.

Description: 

The transposition of atoms or groups in the purine nucleobase of G/dG provides isomers that have altered base-pairing capabilities.  We offer a family of guanosine isomers in nucleoside and phosphoramidite forms.

Pseudo-dG (PRA 10103) is a guanosine isomer that was recently reported by Hosmane and co-workers.1  We also offer Pseudo-dG CEP (BA 0312) , which may be used to incorporate Pseudo-dG nucleotides into DNA.

Pseudo-dG and Pseudo-dG CEP are part of a family that includes Guanosine (PR 3703) , 2'-Deoxyguanosine (PR 3452) , the isomeric nucleosides Isoguanosine (Iso-G, PR 3735) , 2'-Deoxyisoguanosine (Iso-dG, PR 3465) , 2'-Deoxypseudoisoguanosine (Pseudoiso-dG, PRA 10104) , and the phosphoramidite Pseudoiso-dG CEP (BA 0314).

Learn more about these novel compounds and their use by downloading a Product Information sheet for our family of guanosine isomers .

1. Ujjinamatada, R. K.; Paulman, R. L.; Ptak, R. G.; Hosmane, R. S. Bioorg. Med. Chem. 2006, 14, 6359-6367.  See also: Ujjinamatada, R. K.; Phatak, P.; Burger, A. M.; Hosmane, R. S. J. Med. Chem. 2008, 51, 694-698.

2'-Deoxypseudoguanosine
Product Details Product Pricing

MF: C10H13N5O4

MW: 267.24

CAS NO: 912814-74-5

Storage Conditions: 20 oC

Purity≥97%

Availability: 

Stock maintained. Ships within 1-3 days.

Alternate Name: 

Pseudo-dG
Unit Weight Unit Price Quantity
10 mg $155.00
50 mg $695.00
 
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